Home » Medical and Health Science » MODELLING AND SIMULATION OF THE SPREAD OF HBV DISEASE WITH INFECTIOUS LATENT
MODELLING AND SIMULATION OF THE SPREAD OF HBV DISEASE WITH INFECTIOUS LATENT
Sold By: Joe Project Store | Item Type: Project Material | Report this? | Attributes: 50 pages | 1-5 chapters | Amount: ₦5,000 | 4 orders. | Marked useful: 5,326 times
INSTANT PROJECT MATERIAL DOWNLOADCHAPTER ONE
1.0 INTRODUCTION
1.1 BACKGROUND OF STUDY
The spread of the HBV in Nigeria has posed a lot of threat to health and well being citizens in Nigeria. It is evident that about a third of the world’s population, approximately 2 billion people gets infected with hepatitis B virus in their life time. About 360 million people remain chronically infected carriers of the disease, most of whom are unaware of their HBV status and about 20% - 30% of whom will eventually die from chronic sequel. The prevalence of HBV infection varies from country to country, depending upon a complex behavioral, environmental and host factors. Chronic HBV can lead to hepatocellular carcinoma after 20 years among persons with chronic HBV infection; the risk for premature death from cirrhosis or hepatocellular carcinoma is 15% - 25%.
Hepatitis B is a disease that is characterized by inflammation of the liver and is caused by infection by the hepatitis B virus. According to (WHO, 2002) stated that hepatitis may be caused by drugs or viral agents; these viral agents include the hepatitis A, B, C, D, E, F, G and H viruses. Hepatitis B is one of the world’s most serious health problems. More than a billion people around the world have serological indicators of past or present infection with hepatitis B virus (HBV).
According to (White and Fenner (1994), Platkov et al (2001), Carriapa et al (2004), Fernandez et al (2006), Onuzulike and Ogueri (2007)) in their research stated that Over 300 million people are chronic carriers of the virus. The fast spread of HBV shows that is very communicable.
It is evident according to (WHO, 2002) that HBV infection can be transmitted from mother to child (vertical), contact with an infected person (horizontal transmission), sexual contact (homosexual and heterosexual transmission) with infected partners, exposure to blood or other infected fluids and contact with HBV contaminated instruments
HBV control measures include vaccination, education, screening of blood and blood products; and treatment (CDC, 2005).
According to (Anderson and May, 1991) stated that epidemiological models help to capture infection or disease transmission mechanisms in a population in a mathematical frame-work in order to predict the behavior of the disease spread through the population.
1.2 STATEMENT OF PROBLEM
What really instigated the study was the massive spread of HBV in Nigeria and most of the African countries. Several efforts has been put in place by the federal government of Nigeria and world health organization (WHO) through the ministry of health in Nigeria to combat HBV.
Secondly mathematicians all over the world have come with up with several model to help solve the model and simulate the spread of HBV; there have been a lot of failed model.
1.3 AIMS AND OBJECTIVES OF STUDY
The main aim of the research work is evaluate the modeling and simulation of the spread of HBV with infectious latent. Other specific objectives of the study include:
1. To find the existence and uniqueness of the solution to the model
2. To carry out sensitivity analysis on Ro to ascertain which parameter that is most sensitive and that should be targeted by way of intervention.
3. To examine the local stability of the model equation using the modified implicit function theorem
1.4 RESEARCH QUESTION
The study came up with research questions so as to ascertain the above stated objectives. The research questions are stated below as follows:
1. How to find the existence and uniqueness of the solution to the model?
2. How to carry out sensitivity analysis on Ro to ascertain which parameter that is most sensitive and that should be targeted by way of intervention?
3. How to perform the local stability of the model equation using the modified implicit function theorem?
1.5 SIGNIFICANT OF STUDY
The study on modeling and simulating of the spread of HBV disease with infectious latent will be of immense benefit to the ministry of health of Nigeria, the World health organization (WHO) and other researchers that wishes to carryout similar research on the above topic as it will discuss the local stability of the model equation using the modified implicit function theorem and also sensitivity analysis on Ro to ascertain which parameter that is most sensitive and that should be targeted by way of intervention
1.6 SCOPE OF STUDY
The study on modeling and simulation of the spread of HBV disease with infectious latent will cover the areas of local stability of the model equation and implicit function theorem
1.7 DEFINITION OF TERMS
HBV: Hepatitis B virus is a viral infection that attacks the liver and can cause both acute and chronic disease. The virus is transmitted through contact with the blood or other body fluids of an infected person.
Tags: Infectious latent Impact of infectious latent Evaluation of infectious latent Assessment of infectious latent Optimization of infectious latent
This material content is developed to serve as a GUIDE for students to conduct academic research
DOWNLOAD THIS PROJECT MATERIAL NOW!
Advertise Here
Not what you were looking for? Perform a search
What's your project topic?
Comment on Facebook:
Related Project Materials
- 1.
INCIDENCE OF SURGICAL SITE INFECTIONS (SSIS) AMONG PATIENTS UNDERGOING MAJOR SURGERY IN NIGERIA: A C...
CHAPTER ONE INTRODUCTION 1.1 Background of the study Statistically, surgical site infections (SSIs) are a prevalent type of hospital acquired infec...More »
Item Type: Project Material | 54 pages | 1,386 engagements |
- 2.
AN ASSESSMENT OF THE RISK FACTORS ASSOCIATED WITH SURGICAL SITE INFECTION
CHAPTER ONE INTRODUCTION 1.1 Background of the study Globally, surgical site infections (SSIs) provide a significant risk of sickness for patients ...More »
Item Type: Project Material | 54 pages | 1,107 engagements |
- 3.
ACCESSIBILITY AND USAGE OF COMBINED ORAL CONTRACEPTIVE AMONG WOMEN OF CHILD BEARING AGE IN GWARINPA,...
CHAPTER ONE INTRODUCTION Background of the Study There have been substantial changes in the worldwide reproductive health situation, with a growing fo...More »
Item Type: Project Material | 54 pages | 690 engagements |
- 4.
INVESTIGATING THE FACTORS INFLUENCING THE ADOPTION OF TELEHEALTH SERVICES IN NIGERIA
CHAPTER ONE INTRODUCTION Background of the Study Telehealth has been described as health care provided remotely to a patient in a separate location...More »
Item Type: Project Material | 54 pages | 1,519 engagements |
- 5.
ASSESSMENT OF THE KNOWLEDGE AND PRACTICE OF TELEMEDICINE AMONG MEDICAL DOCTORS IN UNIVERSITY OF NIGE...
CHAPTER ONE INTRODUCTION Background of the study The adoption of telehealth has experienced a substantial increase in reaction to the COVID 19 epidemi...More »
Item Type: Project Material | 54 pages | 975 engagements |
- 6.
ASSESSING THE CHALLENGES AND BENEFITS OF TELEHEALTH SERVICES IN NIGERIA
CHAPTER ONE INTRODUCTION Background of the Study Globally, the healthcare system has been over stretched in the face of epidemics and pandemics as a r...More »
Item Type: Project Material | 54 pages | 907 engagements |